right ventricular systolic pressure rvsp Search Results


99
ADInstruments right ventricular systolic pressure rvsp
FTS•B relieved MCT-induced PAH and vascular remodeling in rats. Rats received intraperitoneal injection of MCT with/without cotreatment with FTS•B. ( A ) Echocardiographic PW Doppler tracing of pulmonary artery outflow. PAT, PET and quantitative PAT and PAT/PET data (n = 6). ( B ) RVFWT and RVEDD in M-mode echo and quantitative data of RVFWT and RVEDD (n = 6). Quantitative analysis of the mPAP ( C ) and <t>RVSP</t> ( D ) (n = 6). ( E ) Survival curves of the rats during the 21-day period (n = 20). ( F ) Representative images of H&E staining of heart sections (scale bar = 2 mm) and quantitative analysis of the RV/ (LV + S) (n = 6). ( G ) Representative images of H&E staining of lung sections (scale bar = 50 μm) and quantitative analysis of the WT (n = 6). ( H ) Representative images of α-SMA immunohistochemical staining of the pulmonary artery (scale bar = 50 μm). 10–20 pulmonary arteries were quantified per rats and quantitative assessments of muscularized distal arterioles (diameter 25–100 μm, n = 6). ( I ) Representative images of PCNA immunohistochemical staining of the pulmonary artery (scale bar = 50 μm) and quantitative analysis of PCNA-positive cells in the pulmonary artery (n = 6). The data are presented as the mean ± SD. * p < 0.05, ** p < 0.01.
Right Ventricular Systolic Pressure Rvsp, supplied by ADInstruments, used in various techniques. Bioz Stars score: 99/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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97
ADInstruments ventricular systolic blood pressure rvsp
FTS•B relieved MCT-induced PAH and vascular remodeling in rats. Rats received intraperitoneal injection of MCT with/without cotreatment with FTS•B. ( A ) Echocardiographic PW Doppler tracing of pulmonary artery outflow. PAT, PET and quantitative PAT and PAT/PET data (n = 6). ( B ) RVFWT and RVEDD in M-mode echo and quantitative data of RVFWT and RVEDD (n = 6). Quantitative analysis of the mPAP ( C ) and <t>RVSP</t> ( D ) (n = 6). ( E ) Survival curves of the rats during the 21-day period (n = 20). ( F ) Representative images of H&E staining of heart sections (scale bar = 2 mm) and quantitative analysis of the RV/ (LV + S) (n = 6). ( G ) Representative images of H&E staining of lung sections (scale bar = 50 μm) and quantitative analysis of the WT (n = 6). ( H ) Representative images of α-SMA immunohistochemical staining of the pulmonary artery (scale bar = 50 μm). 10–20 pulmonary arteries were quantified per rats and quantitative assessments of muscularized distal arterioles (diameter 25–100 μm, n = 6). ( I ) Representative images of PCNA immunohistochemical staining of the pulmonary artery (scale bar = 50 μm) and quantitative analysis of PCNA-positive cells in the pulmonary artery (n = 6). The data are presented as the mean ± SD. * p < 0.05, ** p < 0.01.
Ventricular Systolic Blood Pressure Rvsp, supplied by ADInstruments, used in various techniques. Bioz Stars score: 97/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Santa Cruz Biotechnology eosin staining rvsp right ventricular systolic pressure rvhi right ventricular hypertrophy index wa medial wall area wt medial wall
FTS•B relieved MCT-induced PAH and vascular remodeling in rats. Rats received intraperitoneal injection of MCT with/without cotreatment with FTS•B. ( A ) Echocardiographic PW Doppler tracing of pulmonary artery outflow. PAT, PET and quantitative PAT and PAT/PET data (n = 6). ( B ) RVFWT and RVEDD in M-mode echo and quantitative data of RVFWT and RVEDD (n = 6). Quantitative analysis of the mPAP ( C ) and <t>RVSP</t> ( D ) (n = 6). ( E ) Survival curves of the rats during the 21-day period (n = 20). ( F ) Representative images of H&E staining of heart sections (scale bar = 2 mm) and quantitative analysis of the RV/ (LV + S) (n = 6). ( G ) Representative images of H&E staining of lung sections (scale bar = 50 μm) and quantitative analysis of the WT (n = 6). ( H ) Representative images of α-SMA immunohistochemical staining of the pulmonary artery (scale bar = 50 μm). 10–20 pulmonary arteries were quantified per rats and quantitative assessments of muscularized distal arterioles (diameter 25–100 μm, n = 6). ( I ) Representative images of PCNA immunohistochemical staining of the pulmonary artery (scale bar = 50 μm) and quantitative analysis of PCNA-positive cells in the pulmonary artery (n = 6). The data are presented as the mean ± SD. * p < 0.05, ** p < 0.01.
Eosin Staining Rvsp Right Ventricular Systolic Pressure Rvhi Right Ventricular Hypertrophy Index Wa Medial Wall Area Wt Medial Wall, supplied by Santa Cruz Biotechnology, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Millar Inc millar catheter
FTS•B relieved MCT-induced PAH and vascular remodeling in rats. Rats received intraperitoneal injection of MCT with/without cotreatment with FTS•B. ( A ) Echocardiographic PW Doppler tracing of pulmonary artery outflow. PAT, PET and quantitative PAT and PAT/PET data (n = 6). ( B ) RVFWT and RVEDD in M-mode echo and quantitative data of RVFWT and RVEDD (n = 6). Quantitative analysis of the mPAP ( C ) and <t>RVSP</t> ( D ) (n = 6). ( E ) Survival curves of the rats during the 21-day period (n = 20). ( F ) Representative images of H&E staining of heart sections (scale bar = 2 mm) and quantitative analysis of the RV/ (LV + S) (n = 6). ( G ) Representative images of H&E staining of lung sections (scale bar = 50 μm) and quantitative analysis of the WT (n = 6). ( H ) Representative images of α-SMA immunohistochemical staining of the pulmonary artery (scale bar = 50 μm). 10–20 pulmonary arteries were quantified per rats and quantitative assessments of muscularized distal arterioles (diameter 25–100 μm, n = 6). ( I ) Representative images of PCNA immunohistochemical staining of the pulmonary artery (scale bar = 50 μm) and quantitative analysis of PCNA-positive cells in the pulmonary artery (n = 6). The data are presented as the mean ± SD. * p < 0.05, ** p < 0.01.
Millar Catheter, supplied by Millar Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Image Search Results


FTS•B relieved MCT-induced PAH and vascular remodeling in rats. Rats received intraperitoneal injection of MCT with/without cotreatment with FTS•B. ( A ) Echocardiographic PW Doppler tracing of pulmonary artery outflow. PAT, PET and quantitative PAT and PAT/PET data (n = 6). ( B ) RVFWT and RVEDD in M-mode echo and quantitative data of RVFWT and RVEDD (n = 6). Quantitative analysis of the mPAP ( C ) and RVSP ( D ) (n = 6). ( E ) Survival curves of the rats during the 21-day period (n = 20). ( F ) Representative images of H&E staining of heart sections (scale bar = 2 mm) and quantitative analysis of the RV/ (LV + S) (n = 6). ( G ) Representative images of H&E staining of lung sections (scale bar = 50 μm) and quantitative analysis of the WT (n = 6). ( H ) Representative images of α-SMA immunohistochemical staining of the pulmonary artery (scale bar = 50 μm). 10–20 pulmonary arteries were quantified per rats and quantitative assessments of muscularized distal arterioles (diameter 25–100 μm, n = 6). ( I ) Representative images of PCNA immunohistochemical staining of the pulmonary artery (scale bar = 50 μm) and quantitative analysis of PCNA-positive cells in the pulmonary artery (n = 6). The data are presented as the mean ± SD. * p < 0.05, ** p < 0.01.

Journal: Drug Design, Development and Therapy

Article Title: Forsythoside B Mitigates Monocrotaline-Induced Pulmonary Arterial Hypertension via Blocking the NF-κB Signaling Pathway to Attenuate Vascular Remodeling

doi: 10.2147/DDDT.S444605

Figure Lengend Snippet: FTS•B relieved MCT-induced PAH and vascular remodeling in rats. Rats received intraperitoneal injection of MCT with/without cotreatment with FTS•B. ( A ) Echocardiographic PW Doppler tracing of pulmonary artery outflow. PAT, PET and quantitative PAT and PAT/PET data (n = 6). ( B ) RVFWT and RVEDD in M-mode echo and quantitative data of RVFWT and RVEDD (n = 6). Quantitative analysis of the mPAP ( C ) and RVSP ( D ) (n = 6). ( E ) Survival curves of the rats during the 21-day period (n = 20). ( F ) Representative images of H&E staining of heart sections (scale bar = 2 mm) and quantitative analysis of the RV/ (LV + S) (n = 6). ( G ) Representative images of H&E staining of lung sections (scale bar = 50 μm) and quantitative analysis of the WT (n = 6). ( H ) Representative images of α-SMA immunohistochemical staining of the pulmonary artery (scale bar = 50 μm). 10–20 pulmonary arteries were quantified per rats and quantitative assessments of muscularized distal arterioles (diameter 25–100 μm, n = 6). ( I ) Representative images of PCNA immunohistochemical staining of the pulmonary artery (scale bar = 50 μm) and quantitative analysis of PCNA-positive cells in the pulmonary artery (n = 6). The data are presented as the mean ± SD. * p < 0.05, ** p < 0.01.

Article Snippet: Mean pulmonary artery pressure (mPAP) and right ventricular systolic pressure (RVSP) were recorded with PowerLab system (AD Instruments) and calculated using the LabChart software according to the previous experiments.

Techniques: Injection, Staining, Immunohistochemical staining

NF-κB activation blocked the protective effect of FTS•B against PAH and vascular remodeling. Rats were subjected to MCT and FTS•B with/without cotreatment with PMA. ( A ) Representative Western blotting of p-p65, p65, p-IκBα, IκBα, p-IKKα, IKKα, p-IKKβ and IKKβ in lung lysates, and quantitative data of p-p65/p65, p-IκBα/IκBα, p-IKKα/IKKα and p-IKKβ/IKKβ (n = 6). ( B ) Echocardiographic PW Doppler tracing of pulmonary artery outflow and quantitative analysis of PAT and PAT/PET (n = 6). ( C ) RVFWT and RVEDD in M-mode echo and relative quantification (n = 6). ( D ) Quantitative analysis of the mPAP (n = 6). ( E ) Quantitative analysis of the RVSP (n = 6). ( F ) Representative images of H&E staining of heart sections (scale bar = 2 mm) and quantitative analysis of the RV/ (LV + S) (n = 6). ( G ). Representative images of H&E staining of lung sections (scale bar = 50 μm) and quantitative analysis of the WT (n = 6). ( H ) Representative images of α-SMA immunohistochemical staining in the pulmonary artery (scale bar = 50 μm) and quantitative assessments of muscularized pulmonary arteries (n = 6). ( I ) Representative images of PCNA immunohistochemical staining in the pulmonary artery (scale bar = 50 μm) and quantitative data of PCNA-positive cells (n = 6). The data are presented as the mean ± SD. * p < 0.05, ** p < 0.01.

Journal: Drug Design, Development and Therapy

Article Title: Forsythoside B Mitigates Monocrotaline-Induced Pulmonary Arterial Hypertension via Blocking the NF-κB Signaling Pathway to Attenuate Vascular Remodeling

doi: 10.2147/DDDT.S444605

Figure Lengend Snippet: NF-κB activation blocked the protective effect of FTS•B against PAH and vascular remodeling. Rats were subjected to MCT and FTS•B with/without cotreatment with PMA. ( A ) Representative Western blotting of p-p65, p65, p-IκBα, IκBα, p-IKKα, IKKα, p-IKKβ and IKKβ in lung lysates, and quantitative data of p-p65/p65, p-IκBα/IκBα, p-IKKα/IKKα and p-IKKβ/IKKβ (n = 6). ( B ) Echocardiographic PW Doppler tracing of pulmonary artery outflow and quantitative analysis of PAT and PAT/PET (n = 6). ( C ) RVFWT and RVEDD in M-mode echo and relative quantification (n = 6). ( D ) Quantitative analysis of the mPAP (n = 6). ( E ) Quantitative analysis of the RVSP (n = 6). ( F ) Representative images of H&E staining of heart sections (scale bar = 2 mm) and quantitative analysis of the RV/ (LV + S) (n = 6). ( G ). Representative images of H&E staining of lung sections (scale bar = 50 μm) and quantitative analysis of the WT (n = 6). ( H ) Representative images of α-SMA immunohistochemical staining in the pulmonary artery (scale bar = 50 μm) and quantitative assessments of muscularized pulmonary arteries (n = 6). ( I ) Representative images of PCNA immunohistochemical staining in the pulmonary artery (scale bar = 50 μm) and quantitative data of PCNA-positive cells (n = 6). The data are presented as the mean ± SD. * p < 0.05, ** p < 0.01.

Article Snippet: Mean pulmonary artery pressure (mPAP) and right ventricular systolic pressure (RVSP) were recorded with PowerLab system (AD Instruments) and calculated using the LabChart software according to the previous experiments.

Techniques: Activation Assay, Western Blot, Quantitative Proteomics, Staining, Immunohistochemical staining